Parameters of cellular and humoral immunity in experimental hyperthyroidism and its correction.

Abstract

We demonstrate changes in cellular and humoral immunity in animals with experimental hyperthyroidism induced by chronic administration of potassium iodide (KI) solution. KI increased the weight and cellularity of the thymus and spleen and number of antibody-forming cells to sheep red blood cells and modified the relative content of T cell subpopulations. Phytosorption complex LimfoFit modifying cellular and humoral immunity affected only its individual parameters in hyperthyroid animals.

• Authors: M V Robinson, T A Obut, E V Melnikova, V A Trufakin
• Journal: Bulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 156 Issue 4 Pg. 473-5 (Feb 2014) ISSN: 1573-8221 [Electronic] United States
• PMID: 24771430 (Publication Type: Journal Article)

Chemical References

• Immunologic Factors
• Triiodothyronine
• Thyroxine

Topics

• Animals
• Drug Evaluation, Preclinical
• Hyperthyroidism (blood, immunology, therapy)
• Immunity, Cellular
• Immunity, Humoral
• Immunologic Factors (therapeutic use)
• Lymphocyte Count
• Male
• Mice, Inbred CBA
• Sheep
• Spleen (immunology, pathology)
• Thymus Gland (immunology, pathology)
• Thyroxine (blood)
• Triiodothyronine (blood)