Abstract | PURPOSE: The aim of this study was to examine the efficacy and surgical success rates of amniotic membrane (AM) transplantation performed for corneal perforation closure using a novel technique. METHODS: RESULTS: All 6 patients had successful wound closure with 1 surgery. One patient underwent optical keratoplasty later, and 1 patient required combined preserved sclera transplantation. The absolute value of astigmatism decreased to <3.50 diopters (D) 3 months after surgery and to <3.00 D 6 months after surgery in patients with peripheral AM transplants. The visual acuity gradually improved over the first 3 months after surgery, and visual acuity gains were maintained at the 6-month postoperative mark. CONCLUSIONS: The AM transplantation procedure may be an effective option for treating corneal perforations when the wound is circular or irregular, except for incised wounds. Our "Pleats Fold" AM transplantation technique can achieve definite closure and effectively repair wounds of various sizes. Postoperative astigmatic values were acceptable. Therefore, we recommend this procedure for repairing lesions <3 mm in diameter that do not involve the central cornea and that are infection free.
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Authors | Hiroyuki Namba, Mari Narumi, Katsuhiro Nishi, Sakiko Goto, Shion Hayashi, Hidetoshi Yamashita |
Journal | Cornea
(Cornea)
Vol. 33
Issue 6
Pg. 653-7
(Jun 2014)
ISSN: 1536-4798 [Electronic] United States |
PMID | 24763120
(Publication Type: Case Reports, Journal Article)
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Topics |
- Aged
- Aged, 80 and over
- Amnion
(transplantation)
- Corneal Perforation
(surgery)
- Humans
- Male
- Middle Aged
- Ophthalmologic Surgical Procedures
- Treatment Outcome
- Visual Acuity
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