Abstract | OBJECTIVE: MATERIALS AND METHODS: RESULTS: In PPC group, real-time RT-PCR and western-blot analysis showed that eNOS mRNA and peNOS protein increased markedly (P < 0.05); iNOS mRNA and protein decreased significantly (P < 0.05). CONCLUSION: These results indicate that ischemic preconditioning (IPC) of GFPC from DGSND plays a protective role in I/R heart through regulating the eNOS/NO signal pathway, which could increase the eNOS gene expression and decrease the expression of iNOS mRNA.
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Authors | Guo-Qiang Qian, Xia Peng, Chuan Cai, Guo-Ping Zhao |
Journal | Pharmacognosy research
(Pharmacognosy Res)
Vol. 6
Issue 2
Pg. 133-7
(Apr 2014)
ISSN: 0976-4836 [Print] India |
PMID | 24761117
(Publication Type: Journal Article)
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