Atypical polypoid adenomyoma of the uterus. An immunohistochemical study of a case.

Abstract

We studied one case of atypical polypoid adenomyoma of the uerus immunohistochemically using antisera against keratins, vinentin, S-100 protein, desmin and actin. The stromal cells were reactive with anti-actin and antidesmin antibodies suggesting a muscular phenotype and confirming previous ultrastructural data. Immunohistochemical investigations have proved to be useful in differential diagnosis of APA with invasive adenocarcinoma, adenosarcoma and adenofibroma of the endometrium.

• Authors: S Di Palma, D Santini, G Martinelli
• Journal: Tumori (Tumori) Vol. 75 Issue 3 Pg. 292-5 (Jun 30 1989) ISSN: 0300-8916 [Print] United States
• PMID: 2475953 (Publication Type: Case Reports, Journal Article)

Chemical References

• Actins
• Desmin
• S100 Proteins
• Vimentin
• Keratins

Topics

• Actins (metabolism)
• Adenocarcinoma (metabolism)
• Adenofibroma (metabolism)
• Desmin (metabolism)
• Diagnosis, Differential
• Endometriosis (metabolism, pathology)
• Female
• Humans
• Immunohistochemistry
• Keratins (metabolism)
• Middle Aged
• S100 Proteins (metabolism)
• Uterine Neoplasms (metabolism, pathology)
• Vimentin (metabolism)