Abstract | OBJECTIVE: METHODS: Twenty AIDS patients with pharyngeal ulcer were retrospectively analysed to explore its clinical features and mechanism, and to explore the feasible therapeutic methods. RESULTS: The patients generally had severe sore throat and dysphagia for 7 days to 8 months, resulting in significant weight loss. Common therapeutical method does not work. The ulcers developed mainly at vestibule of pharynx (10 cases), tonsil (3 cases), epiglottis (3 cases) and pyriform sinus (2 cases). Ulcer types included major aphthous ulcer (MaAU, 14 cases), fungal ulcer (2 cases), herpes zoster (1 case), ulcer secondary to drug eruption(1 case ), and lymphoma(2 cases). The disease course was long with CD4(+) T lymphocytes decreased significantly. Treatment was given with highly active antiretroviral therapy (HARRT), regulation of immune function, analgesic, anti-inflammatory and anti fungal. Treatment lasted from 2 weeks to 3 months, ulcer healed in 13 cases; 1 patient lost to follow-up, 6 patients dead. CONCLUSIONS:
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Authors | Gaoli Fang, Luo Zhang, Chengshuo Wang, Jiang Xiao, Qian Fu, Hongxin Zhao |
Journal | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
(Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi)
Vol. 49
Issue 2
Pg. 125-30
(Feb 2014)
ISSN: 1673-0860 [Print] China |
PMID | 24742511
(Publication Type: English Abstract, Journal Article)
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Topics |
- Acquired Immunodeficiency Syndrome
(complications)
- Adolescent
- Adult
- Female
- Humans
- Male
- Middle Aged
- Oral Ulcer
(complications, diagnosis)
- Pharyngeal Diseases
(complications, diagnosis)
- Retrospective Studies
- Ulcer
(complications)
- Young Adult
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