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Avascular necrosis of the hip and diffuse idiopathic skeletal hyperostosis during long-term isotretinoin treatment of epidermolytic ichthyosis due to a novel deletion mutation in KRT10.

AuthorsR C Lamb, J Lang, A Terron-Kwiatowski, D Baty, W H I McLean, M Zamiri
JournalThe British journal of dermatology (Br J Dermatol) Vol. 171 Issue 4 Pg. 913-5 (Oct 2014) ISSN: 1365-2133 [Electronic] England
PMID24720725 (Publication Type: Case Reports, Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • Dermatologic Agents
  • KRT10 protein, human
  • Keratin-10
  • Isotretinoin
Topics
  • Adult
  • Dermatologic Agents (adverse effects)
  • Female
  • Hip Joint
  • Humans
  • Hyperkeratosis, Epidermolytic (drug therapy, genetics)
  • Hyperostosis, Diffuse Idiopathic Skeletal (chemically induced, genetics)
  • Isotretinoin (adverse effects)
  • Keratin-10 (genetics)
  • Osteonecrosis (chemically induced, genetics)
  • Sequence Deletion (genetics)

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