Dental sealants and flowable composite restorations and psychosocial, neuropsychological, and physical development in children.

Abstract

PURPOSE:

Dental sealant materials may intraorally release their components, including bisphenol-A (BPA), but long-term health effects are uncertain. The New England Children's Amalgam Trial (NECAT) found that composite restorations were associated with psychosocial, but not neuropsychological or physical, outcomes. The previous analysis did not consider sealants and preventive resin restorations (PRRs), which were routinely placed. The purpose of this analysis was to examine sealant/PRR exposure in association with psychosocial and other health outcomes.

METHODS:

NECAT recruited 534 six- to 10-year-olds and provided dental care during a five-year follow-up. Annually, examiners conducted psychosocial and neuropsychological tests and measured body mass index (BMI) and fat percentage (BF%). Associations between surface years (SY) of sealants/PRRs and outcomes were tested using multivariable models.

RESULTS:

Cumulative exposure level to sealants and/or PRRs was not associated with psychosocial assessments (eg, total problems: Child Behavior Checklist, 10-SY β=-0.2 ± 0.3, P=.60) or neuropsychological tests (eg, full-scale IQ, 10-SY β=0.1 ± 0.2, P=.60). There were no associations for changes in BMI-for-age z-score (P=.40), BF% (girls 10-SY β=-0.2 ± 0.3; boys 10-SY β=-0.1 ± 0.3), or menarche (10-SY hazard ratio=0.91, 95% confidence interval=0.83-1.01, P=.08).

CONCLUSIONS:

This study showed no associations between exposure level of dental sealants or PRRs and behavioral, neuropsychological, or physical development in children over 5-years.

• Authors: Nancy N Maserejian, Peter Shrader, Felicia L Trachtenberg, Russ Hauser, David C Bellinger, Mary Tavares
• Journal: Pediatric dentistry (Pediatr Dent) 2014 Jan-Feb Vol. 36 Issue 1 Pg. 68-75 ISSN: 1942-5473 [Electronic] United States
• PMID: 24717713 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Compomers
• Composite Resins
• Dental Materials
• Dyract Flow Compomer
• Pit and Fissure Sealants
• Revolution (composite resin)
• Ultra Seal XT
• Z100 composite resin
• flowable hybrid composite
• Bisphenol A-Glycidyl Methacrylate
• Silicon Dioxide
• Zirconium

Topics

• Bisphenol A-Glycidyl Methacrylate (chemistry)
• Body Fat Distribution
• Body Mass Index
• Child
• Child Behavior (drug effects)
• Child Development (drug effects)
• Cohort Studies
• Compomers (chemistry)
• Composite Resins (chemistry, therapeutic use)
• Dental Materials (chemistry)
• Dental Restoration, Permanent (classification)
• Environmental Exposure
• Female
• Follow-Up Studies
• Humans
• Intelligence Tests
• Male
• Menarche (drug effects)
• Neuropsychological Tests
• Pit and Fissure Sealants (therapeutic use)
• Psychology, Child
• Silicon Dioxide (chemistry)
• Zirconium (chemistry)