Effectiveness and safety of cryotherapy after arthroscopic anterior cruciate ligament reconstruction. A systematic review of the literature.

Cryotherapy is widely used in rehabilitation; however, its effectiveness after anterior cruciate ligament (ACL) reconstruction remains uncertain. To investigate the effectiveness and safety of cryotherapy following ACL reconstruction through a systematic review, randomized and quasi-randomized clinical trials were searched in the databases: MEDLINE, EMBASE, CENTRAL, PEDro, SportDiscus, CINAHL, LILACS (June 2013). The primary outcomes measures were pain, edema and adverse events; the secondary outcomes were knee function, analgesic medication use, range of motion, blood loss, hospital stay, quality of life and patient satisfaction. The methodological quality of studies was evaluated using the Cochrane Collaboration risk-of-bias tool. Ten trials (a total of 573 patients) were included. Results of meta-analysis showed that the use of cold compression devices produced a significant reduction in pain scores 48 h after surgery (p < 0.00001), compared to no cryotherapy. The risk for adverse events did not differ between patients receiving cryotherapy versus no treatment (p = 1.00). The limited evidence currently available is insufficient to draw definitive conclusions on the effectiveness of cryotherapy for other outcomes. There is a need for well designed, good quality randomized trials to answer other questions related to this intervention and increase the precision of future systematic reviews.
AuthorsAna Luiza Cabrera Martimbianco, Brenda Nazaré Gomes da Silva, Alan Pedrosa Viegas de Carvalho, Valter Silva, Maria Regina Torloni, Maria Stella Peccin
JournalPhysical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine (Phys Ther Sport) Vol. 15 Issue 4 Pg. 261-8 (Nov 2014) ISSN: 1873-1600 [Electronic] England
PMID24713365 (Publication Type: Journal Article, Meta-Analysis, Review)
CopyrightCopyright © 2014 Elsevier Ltd. All rights reserved.
  • Anterior Cruciate Ligament Reconstruction (methods, rehabilitation)
  • Arthroscopy
  • Cryotherapy (methods)
  • Humans
  • Knee Injuries (rehabilitation, surgery)
  • Pain, Postoperative (prevention & control, rehabilitation)
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: