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Keratitis with Kocuria palustris and Rothia mucilaginosa in Vitamin A Deficiency.

AbstractPURPOSE:
To present a case of unusual corneal infection early in the course of peripheral ulcerative keratitis in a patient with severe vitamin A deficiency.
METHOD:
Single observational case report in urban USA.
CASE PRESENTATION:
An alcoholic patient with pancreatitis, chronic diarrhea, and vitamin A deficiency presented with a marginal corneal ulcer from which two bacteria of the family Micrococcaceae were cultured and identified by genome sequence analysis, namely Kocuria palustris and Rothia mucilaginosa. Soon after, severe bilateral peripheral ulcerative keratitis developed, later accompanied by eyelid cellulitis of one lid. These conditions improved with antibiotics, treatment of the underlying gastrointestinal conditions, and treatment of the vitamin deficiency.
CONCLUSION:
Susceptibility to keratitis with unusual bacteria of the Micrococcaceae family can occur in the setting of alcoholism-related gastrointestinal disease with severe vitamin A deficiency. To our knowledge, K. palustris is a species not previously identified in any human disease, and the Kocuria genus has not previously been reported as a participant in eye infection. Documented cases of R. mucilaginosa in ocular disease are rare. These unusual infections heralded the onset of severe marginal corneal melts.
AuthorsR M Mattern, Jiaxi Ding
JournalCase reports in ophthalmology (Case Rep Ophthalmol) Vol. 5 Issue 1 Pg. 72-7 (Jan 2014) ISSN: 1663-2699 [Print] Switzerland
PMID24707276 (Publication Type: Case Reports)

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