Myopericarditis with predominantly right ventricular involvement with normal B-type natriuretic peptide and cardiac tamponade as the initial manifestation of systemic lupus erythematosus.

Abstract

A previously healthy young man presented with a 12-hour history of sudden dyspnea and severe chest pain at rest. Initial findings of physical examination, electrocardiogram and chest radiography showed typical pericarditis and clinical instability. Echocardiogram revealed small pericardial effusion with right ventricle dilatation. The patient was admitted in the ICU; a new echocardiogram revealed moderate pericardial effusion and diagnosis of pericarditis complicated with acute cardiac tamponade was established. The patient transiently improved after pericardial window. In the following hours, the diagnosis of myocarditis with predominantly right ventricular involvement (MPRVI) with severe right heart failure was supported by clinical, chest radiography and echocardiogram data, despite normal B-type natriuretic peptide. On day 2, cardiac troponin I detection was observed. By day 3, B-type natriuretic peptide in the range of ventricular dysfunction was identified. Cardiovascular magnetic resonance findings supported the diagnosis of MPRVI. A systematic MEDLINE/PubMed from 1993 to 2013 does not identify any cases of MPRVI related to systemic lupus erythematosus. Simultaneous acute MPRVI with normal B-type natriuretic peptide and acute cardiac tamponade heralding the diagnosis of systemic lupus erythematosus, to the best of our knowledge, has not been previously described.

• Authors: Luis Manautou, Carlos Jerjes-Sanchez, Manuel Meraz, Luis F Perez-Garcia, Antonio Diaz-Cid, Erasmo de la Peña-Almaguer, Cesar Avila, Luis Sanchez
• Journal: Lupus (Lupus) Vol. 23 Issue 9 Pg. 935-8 (Aug 2014) ISSN: 1477-0962 [Electronic] England
• PMID: 24704777 (Publication Type: Case Reports, Journal Article)
• Copyright: © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Chemical References

• Natriuretic Peptide, Brain

Topics

• Adult
• Cardiac Tamponade (blood, etiology)
• Heart Ventricles
• Humans
• Lupus Erythematosus, Systemic (blood, complications, diagnosis)
• Male
• Myocarditis (blood, etiology)
• Natriuretic Peptide, Brain (blood)
• Pericarditis (blood, etiology)