Abstract | OBJECTIVES: MATERIALS AND METHODS: RESULTS: Combination treatment with Compound Danshen Dripping Pills and human umbilical cord blood mononuclear cell transplant significantly increased the survival of implanted cells, inhibited cardiac cell apoptosis, decreased oxidative stress, decreased the inflammatory response, and improved cardiac function. Rabbits treated with either Compound Danshen Dripping Pills or human umbilical cord blood mononuclear cells alone had improvement in these effects compared with untreated control rabbits. CONCLUSIONS:
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Authors | Yi Jun, Yuan Chunju, Ai Qi, Deng Liuxia, Yu Guolong |
Journal | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
(Exp Clin Transplant)
Vol. 12
Issue 2
Pg. 123-8
(Apr 2014)
ISSN: 2146-8427 [Electronic] Turkey |
PMID | 24702144
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Drugs, Chinese Herbal
- fufang danshen
- Malondialdehyde
- Superoxide Dismutase
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Topics |
- Animals
- Apoptosis
(drug effects)
- Cell Survival
(drug effects)
- Combined Modality Therapy
- Cord Blood Stem Cell Transplantation
- Disease Models, Animal
- Drugs, Chinese Herbal
(pharmacology)
- Female
- Humans
- Male
- Malondialdehyde
(metabolism)
- Myocardial Contraction
(drug effects)
- Myocardial Infarction
(metabolism, pathology, physiopathology, therapy)
- Myocytes, Cardiac
(drug effects, metabolism, pathology)
- Oxidative Stress
(drug effects)
- Rabbits
- Stem Cell Niche
(drug effects)
- Stroke Volume
(drug effects)
- Superoxide Dismutase
(metabolism)
- Ventricular Function, Left
(drug effects)
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