Retinal hemorrhages in intubated pediatric intensive care patients.

Abstract

PURPOSE:

To define the diagnoses associated with the presence of retinal hemorrhages, to clarify the association between retinal hemorrhages, cardiopulmonary resuscitation (CPR), and coagulopathy, and to describe the type of retinal hemorrhages found in intubated critically ill patients <4 years of age.

METHODS:

This was a prospective observational study of intubated patients <4 years of age admitted to the pediatric intensive care unit of a tertiary care center from March 2010 to May 2012. The presence and description of retinal hemorrhages was recorded along with diagnoses, international normalized ratio (INR), CPR (in minutes), and mortality.

RESULTS:

A total of 85 intubated, critically ill patients (37 females) were included; average patient age was 8.2 months (range, 0.1-46.8 months). Of the 85 patients, 6 (7%) had retinal hemorrhages (95% CI, 0.029-0.153). Of the 6 patients with RH, abusive head trauma (AHT) was diagnosed in 4 patients, 1 patient had direct head trauma, and 1 had CPR. There were 8 patients with CPR out of the 85. AHT was highly associated with severe multilayered retinal hemorrhages (P = 0.0001) but coagulopathy (P = 0.2671) and CPR (P = 0.5342) were not.

CONCLUSIONS:

Severe multilayered retinal hemorrhages were associated with AHT in this cohort of patients. Without a history of trauma, retinal hemorrhages occurred in only 1 of 85 patients; in this case the hemorrhages were mild, confined to the posterior pole, and found only in the retinal layer.

• Authors: Susannah Q Longmuir, Lindsay McConnell, Resmiye Oral, Alina Dumitrescu, Sameer Kamath, Gwen Erkonen
• Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus (J AAPOS) Vol. 18 Issue 2 Pg. 129-33 (Apr 2014) ISSN: 1528-3933 [Electronic] United States
• PMID: 24698608 (Publication Type: Journal Article, Observational Study)
• Copyright: Copyright © 2014 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.

Topics

• Child Abuse (diagnosis)
• Child, Preschool
• Craniocerebral Trauma (diagnosis)
• Critical Illness (epidemiology)
• Female
• Hospital Mortality
• Humans
• Infant
• Intensive Care Units, Pediatric (statistics & numerical data)
• Intubation (statistics & numerical data)
• Male
• Prevalence
• Prospective Studies
• Retinal Hemorrhage (diagnosis, epidemiology)