[A case of hepatoma treated successfully with a percutaneous intratumoral injection of CDDP-PC-lipiodol suspension].

Abstract

Reported is a case that was treated successfully with a percutaneous intratumoral injection of a CDDP-PC-Lipiodol Suspension (CPLS) of the viable tumor cells of a hepatoma after arterial injection therapy. Although the size of the viable tumor cells remained almost unchanged, a marked reduction in the level of the plasma AFP (484 ng/ml-35 ng/ml) was obtained after the percutaneous injection. No major complication was encountered except for minimal vomiting and mild transient abnormalities of the liver functions.

• Authors: H Aikawa, H Maeda, A Nakashima, A Ashizawa, H Mori, A Azimu, K Hirao, I Isomoto, Y Matuoka, Y Monzen
• Journal: Gan no rinsho. Japan journal of cancer clinics (Gan No Rinsho) Vol. 35 Issue 5 Pg. 620-4 (Apr 1989) ISSN: 0021-4949 [Print] Japan
• PMID: 2469810 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Phosphatidylcholines
• Surface-Active Agents
• Suspensions
• alpha-Fetoproteins
• Iodized Oil
• Cisplatin

Topics

• Aged
• Carcinoma, Hepatocellular (blood, drug therapy)
• Cisplatin (administration & dosage)
• Drug Tolerance
• Humans
• Injections (methods)
• Iodized Oil (administration & dosage)
• Liver Neoplasms (blood, drug therapy)
• Male
• Phosphatidylcholines (administration & dosage)
• Surface-Active Agents (administration & dosage)
• Suspensions
• alpha-Fetoproteins (metabolism)