Visible light excitable ON fluorescence and naked eye detection of Cu²⁺ via hydrolysis of rhodamine-thiophene conjugate: human breast cancer cell (MCF7) imaging studies.

Abstract

Thiophene appended rhodaminehydrazone derivative, RDHDTCA allows selective colorimetric and fluorescence recognition of Cu(2+) as low as 2.4 × 10(-8) M. RDHDTCA is capable to detect intracellular Cu(2+) in human breast cancer cells, MCF7 under fluorescence microscope.

• Authors: Sangita Adhikari, Abhijit Ghosh, Sandip Mandal, Archya Sengupta, Ansuman Chattopadhyay, Jesús Sanmartín Matalobos, Sisir Lohar, Debasis Das
• Journal: Dalton transactions (Cambridge, England : 2003) (Dalton Trans) Vol. 43 Issue 21 Pg. 7747-51 (Jun 07 2014) ISSN: 1477-9234 [Electronic] England
• PMID: 24695622 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Fluorescent Dyes
• Rhodamines
• Thiophenes
• Copper

Topics

• Breast (chemistry, pathology)
• Breast Neoplasms (chemistry, pathology)
• Colorimetry
• Copper (analysis)
• Female
• Fluorescence
• Fluorescent Dyes (chemistry)
• Humans
• Hydrolysis
• Light
• Microscopy, Fluorescence
• Optical Imaging
• Rhodamines (chemistry)
• Thiophenes (chemistry)