Abstract |
We herein report the case of a 72-year-old woman with diffuse cutaneous systemic sclerosis (SSc) complicated by antineutrophil cytoplasmic antibody ( ANCA)-associated vasculitis who exhibited honeycomb lung without volume loss. On admission, chest computed tomography (CT) revealed honeycomb lung without volume loss in addition to increased density of the partition walls. A renal biopsy revealed global sclerosis and cellular crescent formation. Mononeuritis multiple subsequently occurred, and steroid pulse therapy with cyclophosphamide was administered. Repeat chest CT showed that the honeycomb lung was unchanged; however, overall reduced density of the partition walls was observed. It is necessary to recognise that vasculitis may develop in SSc patients who exhibit honeycomb lung without volume loss.
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Authors | Hiroyuki Yamashita, Yuko Takahashi, Hiroshi Kaneko, Toshikazu Kano, Akio Mimori |
Journal | Internal medicine (Tokyo, Japan)
(Intern Med)
Vol. 53
Issue 7
Pg. 801-4
( 2014)
ISSN: 1349-7235 [Electronic] Japan |
PMID | 24694501
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antibodies, Antineutrophil Cytoplasmic
- Peroxidase
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Topics |
- Aged
- Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
(diagnosis, etiology, immunology)
- Antibodies, Antineutrophil Cytoplasmic
(immunology)
- Diagnosis, Differential
- Fatal Outcome
- Female
- Humans
- Lung Diseases
(diagnosis, etiology)
- Peroxidase
(immunology)
- Scleroderma, Diffuse
(complications, diagnosis, immunology)
- Tomography, X-Ray Computed
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