Abstract |
This report describes a patient with autoimmune myelofibrosis accompanied by Sjögren's syndrome (SS). A 36-year-old woman was admitted due to petechiae, purpura, gingival bleeding, dyspnea on exertion, and a lack of concentration. She had pancytopenia and was diagnosed with SS. A bone marrow study showed hypercellular marrow with reticulin fibrosis. Lymphocytic infiltrates and aggregates composed of a mixture of T and B cells in the marrow were also observed. A chromosomal analysis of the marrow cells showed 47, XXX and an analysis of peripheral lymphocytes revealed 47, XXX/46, XX mosaic results. The patient's cytopenia resolved following treatment with oral prednisolone.
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Authors | Tohru Takahashi |
Journal | Internal medicine (Tokyo, Japan)
(Intern Med)
Vol. 53
Issue 7
Pg. 783-7
( 2014)
ISSN: 1349-7235 [Electronic] Japan |
PMID | 24694497
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Glucocorticoids
- Prednisolone
|
Topics |
- Adult
- Chromosomes, Human, X
(genetics)
- Female
- Follow-Up Studies
- Genetic Testing
- Glucocorticoids
(therapeutic use)
- Humans
- Prednisolone
(therapeutic use)
- Primary Myelofibrosis
(complications, diagnosis, drug therapy)
- Sex Chromosome Aberrations
- Sex Chromosome Disorders of Sex Development
(complications, genetics)
- Sjogren's Syndrome
(complications, diagnosis)
- Tomography, X-Ray Computed
- Trisomy
(genetics)
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