Partial internal biliary diversion in progressive familial intrahepatic cholestasis: introduction of a new approach.

Abstract

INTRODUCTION:

Facilitation of biliary salts secretion represents the mainstay of treatment for progressive familial intrahepatic cholestasis (PFIC). The purpose of this study was to introduce a new approach for the treatment of progressive familial intrahepatic cholestasis (PFIC) to avoid ostoma.

CASE PRESENTATION:

An 11-year-old girl with the diagnosis of PFIC underwent cholecystoappendicostomy with myotomy operation. Because of anastomosis stricture, she was reoperated with cholecystojejunocolic anastomosis and intussuscepted valve surgery. She was followed for 9 months. Despite disappointing outcomes of internal drainage with cholecystoappendicostomy, results of cholecystojejunocolic anastomosis with intussuscepted valve surgery were promising.

DISCUSSION:

The cholecystojejunocolic anastomosis with intussuscepted valve surgery could be considered as a forthcoming approach in the treatment of intrahepatic cholestasis.

• Authors: Seyed Abdollah Mousavi, Hasan Karami
• Journal: Hepatitis monthly (Hepat Mon) Vol. 14 Issue 3 Pg. e13549 (Mar 2014) ISSN: 1735-143X [Print] Netherlands
• PMID: 24693315 (Publication Type: Case Reports)