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Incidence of mucositis in patients treated with temsirolimus-based regimens and correlation to treatment response.

AuthorsXiaochun Liu, Patricia Lorusso, Monica Mita, Sarina Piha-Paul, David S Hong, Siqing Fu, Lacey McQuinn, Ekaterine Asatiani, Lawrence A Doyle, Helen X Chen, Kenneth R Hess, Razelle Kurzrock, Aung Naing
JournalThe oncologist (Oncologist) Vol. 19 Issue 4 Pg. 426-8 (Apr 2014) ISSN: 1549-490X [Electronic] England
PMID24668327 (Publication Type: Clinical Trial, Phase I, Journal Article, Research Support, N.I.H., Extramural)
Chemical References
  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents
  • N-(2,3-dihydroxypropyl)-1-((2-fluoro-4-iodophenyl)amino)isonicotinamide
  • Protein Kinase Inhibitors
  • cixutumumab
  • Niacinamide
  • temsirolimus
  • Metformin
  • MTOR protein, human
  • TOR Serine-Threonine Kinases
  • Sirolimus
Topics
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antibodies, Monoclonal (therapeutic use)
  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents (adverse effects, therapeutic use)
  • Antineoplastic Combined Chemotherapy Protocols (adverse effects, therapeutic use)
  • Female
  • Humans
  • Male
  • Metformin (therapeutic use)
  • Middle Aged
  • Mucositis (chemically induced, epidemiology)
  • Niacinamide (analogs & derivatives, therapeutic use)
  • Protein Kinase Inhibitors (adverse effects, therapeutic use)
  • Retrospective Studies
  • Sirolimus (adverse effects, analogs & derivatives, therapeutic use)
  • TOR Serine-Threonine Kinases (antagonists & inhibitors)
  • Treatment Outcome
  • Young Adult

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