Abstract | OBJECTIVES: The purpose of the present study was to ascertain whether pediatric patients with chronic abdominal pain had concurrent fructose intolerance as determined by a standardized dose breath hydrogen test ( BHT), and whether symptoms would improve with a low- fructose diet. METHODS: The fructose BHT test was administered to patients evaluated in clinic with unexplained chronic abdominal pain alone or associated with constipation, gas or bloating, and/or diarrhea. The patients were given a standard dose of 1 g/kg fructose to maximum of 25 g. Hydrogen and methane were measured at 8 time points. The test was presumed positive if breath hydrogen exceeded 20 ppm above baseline. If positive, patients were given a dietitian-prescribed low- fructose diet. RESULTS: A total of 222 patients were part of the study. Ages ranged from 2 to 19 years with a mean of 10.5. BHT for fructose was performed in all of the patients and it was positive for fructose intolerance in 121 of 222 patients (54.5%). A total of 101 of 222 (45.5%) patients had negative BHT for fructose intolerance. All BHT-positive patients had a nutrition consult with a registered dietitian and were placed on a low- fructose diet. Using a standard pain scale for children, 93 of 121 patients (76.9%) reported resolution of symptoms on a low- fructose diet (P < 0.0001). Furthermore, 55 of 101 patients (54.4%) with negative BHT for fructose reported resolution of symptoms without a low- fructose diet (P = 0.37). CONCLUSIONS:
|
Authors | Mauricio A Escobar Jr, Daniel Lustig, Bethann M Pflugeisen, Paul J Amoroso, Dalia Sherif, Rasha Saeed, Shaza Shamdeen, Judith Tuider, Bisher Abdullah |
Journal | Journal of pediatric gastroenterology and nutrition
(J Pediatr Gastroenterol Nutr)
Vol. 58
Issue 4
Pg. 498-501
(Apr 2014)
ISSN: 1536-4801 [Electronic] United States |
PMID | 24667867
(Publication Type: Journal Article)
|
Chemical References |
- Dietary Carbohydrates
- Fructose
- Hydrogen
- Methane
|
Topics |
- Abdominal Pain
(etiology)
- Adolescent
- Breath Tests
- Child
- Child, Preschool
- Dietary Carbohydrates
(administration & dosage)
- Female
- Fructose
(administration & dosage)
- Fructose Intolerance
(complications, diagnosis, diet therapy)
- Humans
- Hydrogen
(analysis)
- Malabsorption Syndromes
(complications, diagnosis, diet therapy)
- Male
- Methane
(analysis)
- Pain Measurement
- Recurrence
- Retrospective Studies
- Young Adult
|