Mechanical performance of a biocompatible biocide soda-lime glass-ceramic.

Abstract

A biocompatible soda-lime glass-ceramic in the SiO2-Na2O-Al2O3-CaO-B2O3 system containing combeite and nepheline as crystalline phases, has been obtained at 750°C by two different routes: (i) pressureless sintering and (ii) Spark Plasma Sintering. The SPS glass-ceramic showed a bending strength, Weibull modulus, and toughness similar values to the cortical human bone. This material had a fatigue limit slightly superior to cortical bone and at least two times higher than commercial dental glass-ceramics and dentine. The in vitro studies indicate that soda-lime glass-ceramic is fully biocompatible. The in vivo studies in beagle jaws showed that implanted SPS rods presented no inflammatory changes in soft tissues surrounding implants in any of the 10 different cases after four months implantation. The radiological analysis indicates no signs of osseointegration lack around implants. Moreover, the biocide activity of SPS glass-ceramic versus Escherichia coli, was found to be >4log indicating that it prevents implant infections. Because of this, the SPS new glass-ceramic is particularly promising for dental applications (inlay, crowns, etc).

• Authors: S López-Esteban, J F Bartolomé, L A Dí Az, L Esteban-Tejeda, C Prado, R López-Piriz, R Torrecillas, J S Moya
• Journal: Journal of the mechanical behavior of biomedical materials (J Mech Behav Biomed Mater) Vol. 34 Pg. 302-12 (Jun 2014) ISSN: 1878-0180 [Electronic] Netherlands
• PMID: 24667693 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2014 Elsevier Ltd. All rights reserved.

Chemical References

• Calcium Compounds
• Coated Materials, Biocompatible
• Disinfectants
• Minerals
• Oxides
• soda lime
• Sodium Hydroxide
• Glass ceramics

Topics

• Animals
• Calcium Compounds (chemistry, metabolism, pharmacology)
• Ceramics (chemistry)
• Coated Materials, Biocompatible (chemistry, metabolism, pharmacology)
• Disinfectants (chemistry, metabolism, pharmacology)
• Dogs
• Escherichia coli (drug effects)
• Humans
• Materials Testing
• Mechanical Phenomena
• Minerals (chemistry)
• Oxides (chemistry, metabolism, pharmacology)
• Saliva (metabolism)
• Sodium Hydroxide (chemistry, metabolism, pharmacology)