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Treatment of metastatic lipid cell tumor of the ovary with BV-CAP and VAC chemotherapy, using serum testosterone and dihydrotestosterone as tumor markers.

Abstract
A metastatic ovarian lipid cell tumor was treated with BV-CAP chemotherapy following cytoreductive surgery and VAC chemotherapy for persistent disease found at second-look laparotomy before disease progression was noted. Serum Dihydrotestosterone (DHT) levels correlated with disease status during all phases of treatment, as did serum testosterone (T) to a lesser degree. Measurement of these two hormones may provide additional useful information on the response of patients with subclinical metastatic disease to post-operative therapy.
AuthorsB Patsner, M S Piver
JournalEuropean journal of gynaecological oncology (Eur J Gynaecol Oncol) Vol. 9 Issue 6 Pg. 441-4 ( 1988) ISSN: 0392-2936 [Print] Singapore
PMID2466668 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Biomarkers, Tumor
  • Dihydrotestosterone
  • Bleomycin
  • Dactinomycin
  • Testosterone
  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Cisplatin
Topics
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Biomarkers, Tumor (blood)
  • Bleomycin (administration & dosage)
  • Cisplatin (administration & dosage)
  • Cyclophosphamide (administration & dosage)
  • Dactinomycin (administration & dosage)
  • Dihydrotestosterone (blood)
  • Doxorubicin (administration & dosage)
  • Female
  • Humans
  • Lipoma (blood, drug therapy)
  • Middle Aged
  • Neoplasm Metastasis
  • Ovarian Neoplasms (blood, drug therapy)
  • Testosterone (blood)
  • Vincristine (administration & dosage)

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