[Effectivity and satisfaction with the treatment for dyslipidemia with pitavastatin. Multicentric, descriptive, post authorised and observational study (REINA study)].

Abstract

INTRODUCTION:

Evaluating the therapeutical adherence as well as the patient' satisfaction with the treatment should be considered to optimize lipidic control. The REINA Study evaluates the grade of satisfaction in dyslipidemic patients treated with pitavastatin.

METHODS:

The current study was observational, descriptive, transversal and multi-centric with patients from our country only. The following data were collected in each case: Morisky-Green test and TSQM-9 for patients older than 18 years old, with dyslipidemia treated with pitavastatin in the last 12 weeks.

RESULTS:

We studied 6,489 patients (60.0% males) from Primary Health (52.7%) and Specialised Health (47.3%), with age (mean) = 60.9 ± 11.2 years by aleatory sampling. 72.3% of patients achieved an adequate control with 2mg/day of pitavastatin. General satisfaction with the treatment was 73.20 points (95% CI: 58.17-87.23). Patients who followed the treatment (65%) showed better data of satisfaction with the drug (77.70 [95% CI: 65.20-90.20]), of global satisfaction (75.00 [95% CI: 61.50-88.50]) and their satisfaction with the drug efficiency was higher (72.50 [95% CI: 57.70-87.30]) than in the patients who did not finish the treatment (72.70 [95% CI: 59.30-85.74]; 68.5 [95% CI: 53.20-83.80] and 67.80 [95% CI: 53.70-81.90], respectively), P < .0001, without any difference between the two primary care systems.

CONCLUSIONS:

The validation of the satisfaction is a crucial indicator in the evaluation of the services offered in health. Patients with the highest grade of satisfaction present better therapeutical adherence, and such a relation is bidirectional. The individuals who are satisfied and who followed the treatment obtained better clinical results. Pitavastatin is an effective therapeutic alternative for patients with dyslipidemia.

• Authors: Luis Alberto Rodríguez Arroyo, Angel Díaz Rodríguez, Xavier Pintó Sala, Antonio Coca Payeras, Joan Rius Tarruella
• Journal: Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis (Clin Investig Arterioscler) 2014 Sep-Oct Vol. 26 Issue 5 Pg. 205-17 ISSN: 1578-1879 [Electronic] Spain
• Vernacular Title: Efectividad y satisfacción del tratamiento de la dislipidemia con pitavastatinastudio observacional, postautorización, descriptivo y multicéntrico (estudio REINA).
• PMID: 24656917 (Publication Type: English Abstract, Journal Article, Multicenter Study)
• Copyright: Copyright © 2013 Sociedad Española de Arteriosclerosis. Published by Elsevier España. All rights reserved.

Chemical References

• Hydroxymethylglutaryl-CoA Reductase Inhibitors
• Quinolines
• pitavastatin

Topics

• Aged
• Cross-Sectional Studies
• Dyslipidemias (drug therapy)
• Female
• Humans
• Hydroxymethylglutaryl-CoA Reductase Inhibitors (administration & dosage, therapeutic use)
• Male
• Medication Adherence
• Middle Aged
• Patient Satisfaction
• Quinolines (administration & dosage, therapeutic use)
• Treatment Outcome