Resolution of recalcitrant pyogenic granuloma with laser, corticosteroid, and timolol therapy.

Abstract

A pyogenic granuloma (PG) is a rapidly growing benign vascular tumor that can be found on the skin or subcutaneous tissue. While some pyogenic granulomas may resolve spontaneously, most have a tendency to bleed easily and require treatment. Current therapeutic modalities include topical imiquimod, cryotherapy, electrodessication, curettage, excision, laser therapy, sclerotherapy, and microembolization. We report a recalcitrant case of chronic pyogenic granuloma occurring on the scalp of a healthy young male which was unresponsive to conventional surgical and non-surgical modalities. Ultimately, aggressive laser therapy, intralesional triamcinolone acetonide injections, and topical timolol application led to complete resolution and healing.

• Authors: Jillian Wong Millsop, Nhat Trinh, Laura Winterfield, Ricado Berrios, Kelli A Hutchens, Rebecca Tung
• Journal: Dermatology online journal (Dermatol Online J) Vol. 20 Issue 3 (Mar 17 2014) ISSN: 1087-2108 [Electronic] United States
• PMID: 24656264 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adrenal Cortex Hormones
• Aminoquinolines
• Anti-Bacterial Agents
• Timolol
• Triamcinolone Acetonide
• Imiquimod

Topics

• Administration, Cutaneous
• Adrenal Cortex Hormones (therapeutic use)
• Adult
• Aminoquinolines (therapeutic use)
• Anti-Bacterial Agents (therapeutic use)
• Biopsy
• Chemotherapy, Adjuvant
• Combined Modality Therapy
• Drug Therapy, Combination
• Granuloma, Pyogenic (diagnosis, drug therapy, pathology, surgery)
• Humans
• Imiquimod
• Laser Therapy
• Lasers, Dye (therapeutic use)
• Lasers, Solid-State (therapeutic use)
• Male
• Recurrence
• Scalp Dermatoses (drug therapy, therapy)
• Timolol (therapeutic use)
• Triamcinolone Acetonide (administration & dosage, therapeutic use)