[Pneumococcal meningitis in a pregnant woman].

Abstract

Bacterial meningitis is a life-threatening disease. The incidence of meningitis is about 2.6-6 cases per 100.000 adults per year in developed countries. The most common causative microorganisms are Sreptococcus pneumoniae and Neisseria meningitidis. A 33-year-old multigravida, at 24 week of gestation was admitted to the hospital because of ear pain, haedache, fever and confusion. Lumbal puncture was performed and cerebrospinal fluid analysis showed signs of bacterial meningitis. Latex agglutination test was positive for S. pneumoniae, Gram-positive diplococci have seen under microscope and later cultivation verified S. pneumoniae as the causative agent. After ceftriaxon, dexamethasone administration and treatment in intensive care unit, left side mastoidectomy was performed since cranial computed tomography showed acut exacerbation of chronic mastoiditis on the left side. After extubation, mobilisation and 14 days antibiotic treatment the patient, who had residual hearing loss on the left side, was discharged from the hospital. During the treatment the foetal parameters were normal. The patient at 39 week of gestation gave birth to a healthy infant. Forty-eight case reports have been published in this topic around the world until April, 2012. The most common causative agents were S. pneumoniae and Listeria monocytogenes. Because of the little amount of data, it is hard to appreciate the actual incidence and prognosis of this life-threatening illness both for mother and infant. As far as we know this is the first published case report of meningitis during pregnancy in Hungary. By this article we would like to draw attention to the importance of teamwork, of prevention of brain abscess formation and of the removal of the infection's focus.

• Authors: Petra Scharek, Csilla Jekkel, József Budai, Zsuzsanna Szilasi, Frigyes Helferich, Ilona Arva, András Váradi, Erzsébet Létay, Katalin Katona, László Rókusz
• Journal: Ideggyogyaszati szemle (Ideggyogy Sz) Vol. 67 Issue 1-2 Pg. 56-8 (Jan 30 2014) ISSN: 0019-1442 [Print] Hungary
• Vernacular Title: Pneumococcus meningitis várandósság során.
• PMID: 24654448 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Anti-Inflammatory Agents
• Ceftriaxone
• Dexamethasone

Topics

• Adult
• Anti-Bacterial Agents (administration & dosage)
• Anti-Inflammatory Agents (administration & dosage)
• Ceftriaxone (administration & dosage)
• Dexamethasone (administration & dosage)
• Drug Therapy, Combination
• Female
• Humans
• Hungary
• Latex Fixation Tests
• Mastoid (surgery)
• Meningitis, Pneumococcal (diagnosis, therapy)
• Pregnancy
• Pregnancy Complications, Infectious (diagnosis, microbiology, therapy)
• Pregnancy Outcome
• Spinal Puncture
• Streptococcus pneumoniae (isolation & purification)
• Treatment Outcome