[Reamberin optimizes drug therapy in children with acute Epstein-Barr viral infection].

Abstract

The efficacy of a 1.5% reamberin solution possessing detoxicating, antihypoxant, antioxidant, and membrane-protective properties, used as a component of the complex infusion therapy in children with acute Epstein-Barr virus infection, has been estimated. The dynamics of the inflammatory process in children treated by the drug complex including reamberin is characterized by rapid relief of general symptoms, improvement of state, and reduction in length of the febrile period of disease as compared to patients treated with glucose-saline solutions and basic therapy. The administration of reamberin in children contributed to the early elimination of metabolic shifts by the period of convalescence, as evidenced by improvement in some laboratory parameters, including protein-synthesis function of the liver.

• Authors: E B Kasymova, O A Bashkina, Kh M Galimzianov, M G Romantsov, K Zh Engibarian, L P Rodina
• Journal: Eksperimental'naia i klinicheskaia farmakologiia (Eksp Klin Farmakol) Vol. 77 Issue 1 Pg. 26-9 ( 2014) ISSN: 0869-2092 [Print] Russia (Federation)
• PMID: 24649599 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Antiviral Agents
• Reamberin
• Succinates
• Meglumine

Topics

• Adolescent
• Antiviral Agents (administration & dosage)
• Child
• Child, Preschool
• Epstein-Barr Virus Infections (drug therapy, metabolism, pathology)
• Female
• Herpesvirus 4, Human
• Humans
• Infant
• Inflammation (drug therapy, metabolism, pathology, virology)
• Liver (metabolism, pathology)
• Male
• Meglumine (administration & dosage, analogs & derivatives)
• Protein Biosynthesis (drug effects)
• Succinates (administration & dosage)