Suspected chlorpyrifos toxicosis in a llama, and plasma pseudocholinesterase activity in llamas given chlorpyrifos.

Abstract

Five days after treatment with chlorpyrifos, a 1.5-year-old male llama was unable to stand, had saliva flowing from its mouth, and had constricted pupils, hyperglycemia, a metabolic acidosis, and a plasma pseudocholinesterase activity of 111 IU/L. Mean (+/- 1 SD) plasma pseudocholinesterase activity of 29 healthy llamas was 233.76 +/- 51.55 IU/L. Five to 8 days after topical application of chlorpyrifos (25 mg/kg of body weight) to 3 healthy llamas, the pseudocholinesterase activity decreased to 38% to 62% of pretreatment (base-line) activity and returned to within 90% of base-line activity by the 36th to 48th day after treatment.

• Authors: E G Pearson, A M Craig, E D Lassen
• Journal: Journal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 189 Issue 9 Pg. 1062-4 (Nov 01 1986) ISSN: 0003-1488 [Print] United States
• PMID: 2464570 (Publication Type: Case Reports, Journal Article)

Chemical References

• Butyrylcholinesterase
• Cholinesterases
• Chlorpyrifos

Topics

• Animals
• Artiodactyla (blood)
• Butyrylcholinesterase (blood)
• Camelids, New World (blood)
• Chlorpyrifos (poisoning)
• Cholinesterases (blood)
• Female
• Male