[Experimental research and analysis on dielectric properties of blood in anemia mice].

Abstract

The conductivity and permittivity of blood in mice were measured by the AC electrical impedance method at frequency range of 0.1-100MHz, and then the changes of the Cole-Cole parameters of dielectric spectra of blood from phenylhydrazine-induced anemia mice were observed by numerical calculation and curve fitting residual analysis of the Cole-Cole equation. The results showed that hematocrit (Hct) of the mice with phenylhydrazine injection was significantly reduced; the permittivity(epsilon) spectroscopy of blood moved to the low insulating region and its permittivity decreased; conductivity (kappa) spectrum curve of blood moved to the high conductivity zone and conductivity increased; the 2nd characteristic frequency was lower than that in the normal group. There was phenylhydrazine dose dependent in the changes of the Cole-Cole parameters of dielectric spectra of blood.

• Authors: Ben Shen, Quiyan Liang, Weiqi Gao, Chu You, Mengqi Hong, Qing Ma
• Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi (Sheng Wu Yi Xue Gong Cheng Xue Za Zhi) Vol. 30 Issue 6 Pg. 1186-90 (Dec 2013) ISSN: 1001-5515 [Print] China
• PMID: 24645593 (Publication Type: Journal Article)

Topics

• Anemia (blood)
• Animals
• Blood Physiological Phenomena
• Electric Conductivity
• Electric Impedance
• Hematocrit
• Mice