[Preparation of porous material based on alginic acid, containing immobilized terrilytin].

Abstract

A comparative study was conducted on immobilization of terrilytin on alginic acid by attaching the enzyme by ionic or covalent bonds and possible use of such compounds in preparing porous coatings for wound treatment. It was shown possible to prepare a coating with the enzyme activity after radiation sterilization equal to 80-85 per cent of the initial level. Medico-biological investigations proved that the use of the coating in treatment of purulent wounds was efficient.

• Authors: A L Komissarova, V S Iakubovidh, P I Tolstykh, I F Skokova, A D Virnik
• Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] (Antibiot Khimioter) Vol. 33 Issue 10 Pg. 735-9 (Oct 1988) ISSN: 0235-2990 [Print] Russia (Federation)
• Vernacular Title: Poluchenie poristogo materiala na osnove al'ginovoĭ kisloty, soderzhashcheĭ immobilizovannyĭ terrilitin.
• PMID: 2463795 (Publication Type: Journal Article)

Chemical References

• Alginates
• Anti-Infective Agents
• Biocompatible Materials
• Drug Combinations
• Enzymes, Immobilized
• Hexuronic Acids
• amylase, phosphates, proteases drug combinations
• Glucuronic Acid
• Amylases
• Peptide Hydrolases

Topics

• Alginates
• Amylases
• Animals
• Anti-Infective Agents
• Biocompatible Materials (chemical synthesis)
• Drug Combinations
• Enzymes, Immobilized
• Glucuronic Acid
• Hexuronic Acids
• Peptide Hydrolases
• Rats
• Wound Healing (drug effects)