Intra-venous chlorpromazine with fluid treatment in status migrainosus.

Abstract

OBJECTIVE:

To present the results of the intra-venous chlorpromazine with fluid treatment in patients with status migrainosus.

METHODS:

Consecutive 21 patients with status migrainosus were received intra-venous chlorpromazine (maximum 25mg) with fluid treatment and their results were documented.

RESULTS:

Complete recovery of headache and nausea were seen in 20/21 and 17/21 of the patients respectively. 15/21 of patients were headache free following at 10mg chlorpromazine infusion. Most patients went on sleep after 10mg chlorpromazine infusion and when they wake already up headache free. Side effects such as tachycardia, palpitation, flushing and hypertension were seen only one of 21 patients following first dose 5mg injection.

CONCLUSIONS:

This study showed that intra-venous chlorpromazine with fluid treatment for status migrainosus seems a good option.

• Authors: Uygar Utku, Mustafa Gokce, Elif Muruvvet Benli, Aytaç Dinc, Deniz Tuncel
• Journal: Clinical neurology and neurosurgery (Clin Neurol Neurosurg) Vol. 119 Pg. 4-5 (Apr 2014) ISSN: 1872-6968 [Electronic] Netherlands
• PMID: 24635917 (Publication Type: Journal Article)
• Copyright: Copyright © 2014 Elsevier B.V. All rights reserved.

Chemical References

• Antiemetics
• Chlorpromazine

Topics

• Administration, Intravenous
• Adult
• Antiemetics (therapeutic use)
• Chlorpromazine (therapeutic use)
• Cohort Studies
• Female
• Fluid Therapy (methods)
• Humans
• Male
• Migraine Disorders (therapy)
• Prospective Studies
• Treatment Outcome