Abstract | INTRODUCTION: CASE: CONCLUSIONS: Given the expanding use of capecitabine, physicians should be aware of this potential complication when a neurological worsening occurs during or after treatment with this chemotherapeutic agent. In our case, as in previously described cases encephalopathy was characterized by a favorable course after cessation of the drug. Vasogenic edema rather than cytotoxic edema may play a pivotal pathogenetic role in this form of encephalopathy.
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Authors | E Lyros, S Walter, I Keller, P Papanagiotou, K Fassbender |
Journal | Neurotoxicology
(Neurotoxicology)
Vol. 42
Pg. 8-11
(May 2014)
ISSN: 1872-9711 [Electronic] Netherlands |
PMID | 24631316
(Publication Type: Case Reports, Journal Article, Review)
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Copyright | Copyright © 2014 Elsevier Inc. All rights reserved. |
Chemical References |
- Prodrugs
- Deoxycytidine
- Capecitabine
- Fluorouracil
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Topics |
- Aged
- Brain Edema
(chemically induced, complications, pathology)
- Capecitabine
- Deoxycytidine
(adverse effects, analogs & derivatives)
- Fluorouracil
(adverse effects, analogs & derivatives)
- Humans
- Magnetic Resonance Imaging
- Male
- Neuroimaging
- Neurotoxicity Syndromes
(complications, pathology)
- Prodrugs
(adverse effects)
- White Matter
(drug effects, pathology)
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