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Wait-and-see policy versus cholecystectomy after endoscopic sphincterotomy for bile-duct stones in high-risk patients with co-existing gallbladder stones: a prospective randomised trial.

AbstractBACKGROUND AND STUDY AIMS:
Endoscopic sphincterotomy (ES) is one of the most important advances in the treatment of common bile duct (CBD) stones. However, the use of ES to remove CBD stones in high-risk patients without cholecystectomy is still debatable. The aim of this study was to compare the efficacy of a wait-and-see policy versus cholecystectomy after ES for CBD stones in high-risk patients with co-existing cholelithiasis.
PATIENTS AND METHODS:
A total of 162 patients after undergoing ES with the clearance of CBD stones were randomised after informed consent to cholecystectomy or conservative management of their gallbladder stones.
RESULTS:
The results indicated that cholecystectomy after ES for CBD stones significantly reduced the biliary complications in high-risk patients.
CONCLUSION:
Every patient who has both CBD stones and gallstones with significant co-morbid illnesses, after clearance of CBD stones by ES, should undergo early cholecystectomy.
AuthorsShowkat A Zargar, Mosin Mushtaq, Mashkoor A Beg, Gul Javaid, Bashir A Khan, Rayhana Hassan, Reyaz A Kasana, Sameena Tabassum
JournalArab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology (Arab J Gastroenterol) Vol. 15 Issue 1 Pg. 24-6 (Mar 2014) ISSN: 2090-2387 [Electronic] Egypt
PMID24630510 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
CopyrightCopyright © 2014 Arab Journal of Gastroenterology. Published by Elsevier Ltd. All rights reserved.
Topics
  • Aged
  • Aged, 80 and over
  • Cholecystectomy (adverse effects)
  • Cholecystolithiasis (complications, therapy)
  • Choledocholithiasis (complications, surgery)
  • Elective Surgical Procedures (adverse effects)
  • Female
  • Humans
  • Male
  • Prospective Studies
  • Risk Factors
  • Sphincterotomy, Endoscopic
  • Watchful Waiting

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