Abstract | BACKGROUND: PATIENTS AND METHODS: RESULTS: Complete response for the acute phase was observed 38/45 (84, 4%) cycles in regimen 1 as compared with 28/31 (90, 3%) in regimen 2, antiemetic cocktail regimen (P > 0.05). Complete response for delayed emesis after 24 h of the beginning of chemotherapy was observed in 29/45 (64, 4 %) in regimen 1 and 16/31 (51, 6%) in regimen 2. Antiemetic cocktail was not superior to the granisetron plus dexamethasone combination in controlling emesis in acute and delayed phase. Furthermore, patients receiving antiemetic regimen 2 were noted significantly more side effects. CONCLUSION: Our data showed that antiemetic cocktail containing midazolam and diphenhydramine was not better in controlling acute and delayed emesis. A slightly more toxicity with additional drugs was also observed.
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Authors | Suna Emir, Pınar Erturgut, Sadi Vidinlisan |
Journal | Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology
(Indian J Med Paediatr Oncol)
Vol. 34
Issue 4
Pg. 270-3
(Oct 2013)
ISSN: 0971-5851 [Print] Germany |
PMID | 24604956
(Publication Type: Journal Article)
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