Intermittent QT prolongation induced by short-term oral amiodarone therapy.

Abstract

Although amiodarone appears to have few pro-arrhythmic effects, torsade de pointes (TdP) has been observed after administration of a low dose and short term use of oral amiodarone, in the absence of predisposing factors. We describe the case of a 41-year-old woman admitted to hospital because of a cardiac arrest from TdP. On hospital admission, ECG showed sinus bradycardia 46 bpm with marked QT prolongation.

• Authors: Mehmet Ali Astarcioglu, Halil Ibrahim Durmuş, Taner Sen, Basri Amasyalı
• Journal: Kardiologia polska (Kardiol Pol) Vol. 72 Issue 2 Pg. 200-1 ( 2014) ISSN: 1897-4279 [Electronic] Poland
• PMID: 24604507 (Publication Type: Journal Article)

Chemical References

• Anti-Arrhythmia Agents
• Amiodarone

Topics

• Administration, Oral
• Adult
• Amiodarone (adverse effects, therapeutic use)
• Anti-Arrhythmia Agents (therapeutic use)
• Brugada Syndrome (chemically induced)
• Cardiac Conduction System Disease
• Electrocardiography
• Female
• Humans
• Long QT Syndrome (chemically induced)
• Torsades de Pointes (drug therapy)