Topical N-acetylcysteine for the treatment of lamellar ichthyosis: an improved formula.

Abstract

Topical N-acetylcysteine is gaining recognition as a useful and safe therapy for lamellar ichthyosis. We report a case of inherited lamellar ichthyosis that showed a good response to treatment with a new formula of N-acetylcysteine cream. With this new formula, which is described in the article in a practical manner, the odor of sulfur was minimized and we obtained excellent adherence to treatment.

• Authors: Paula Davila-Seijo, Angeles Flórez, Carmen Davila-Pousa, Nuria No, Carlos Ferreira, Carlos De la Torre
• Journal: Pediatric dermatology (Pediatr Dermatol) 2014 May-Jun Vol. 31 Issue 3 Pg. 395-7 ISSN: 1525-1470 [Electronic] United States
• PMID: 24602057 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2014 Wiley Periodicals, Inc.

Chemical References

• Free Radical Scavengers
• Acetylcysteine

Topics

• Acetylcysteine (administration & dosage)
• Administration, Topical
• Chemistry, Pharmaceutical (methods)
• Child, Preschool
• Free Radical Scavengers (administration & dosage)
• Humans
• Ichthyosis, Lamellar (drug therapy)
• Male
• Treatment Outcome