Abstract | OBJECTIVES: METHODS: Whole blood manganese concentrations were measured by graphite furnace atomic absorption spectrometry in 21 dogs with primary hepatitis, 65 dogs with a congenital portosystemic shunt, 31 dogs with non-hepatic illnesses and 18 healthy dogs. RESULTS: The whole blood manganese concentrations were significantly different between dogs with primary hepatitis, dogs with non-hepatic illnesses and healthy dogs (P=0·002). Dogs with primary hepatitis had significantly increased whole blood manganese concentrations compared with healthy dogs (P<0·05) and dogs with non-hepatic illnesses (P<0·01). Dogs with primary hepatitis had significantly lower whole blood manganese concentration compared with dogs with congenital portosystemic shunts (P=0·0005). CLINICAL SIGNIFICANCE:
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Authors | S Kilpatrick, A Jacinto, R D Foale, S W Tappin, C Burton, P E Frowde, C M Elwood, R Powell, A Duncan, R J Mellanby, A G Gow |
Journal | The Journal of small animal practice
(J Small Anim Pract)
Vol. 55
Issue 5
Pg. 241-6
(May 2014)
ISSN: 1748-5827 [Electronic] England |
PMID | 24593275
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2014 British Small Animal Veterinary Association. |
Chemical References |
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Topics |
- Animals
- Case-Control Studies
- Dog Diseases
(blood, congenital)
- Dogs
(blood)
- Female
- Hepatitis, Animal
(blood)
- Male
- Manganese
(blood)
- Portal System
(abnormalities)
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