[Effect of terrilytin on the activity of nonspecific resistance factors during immunization with staphylococcal anatoxin and staphylococcal infection].

Abstract	Terrilytin and immobilized terrilytin enhance the activity and intensity of phagocytosis and increase the concentration of lysozyme in nonimmunized animals. Both preparations increase the production of antibodies to staphylococcal alpha-hemolysin, the titers of beta-lysins, the activity and intensity of the phagocytosis of bacterial cells by peripheral blood leukocytes in animals immunized with staphylococcal toxoid and challenged with live staphylococcal culture. In healthy animals terrilytin and immobilized terrilytin induce an increase in total proteolytic activity and in the activity of alpha-1-antitrypsin and alpha-2-macroglobulin, decreased as the result of staphylococcal infection.
Authors	V V Bel'skiĭ, L M Zakarian, L G Prokopenko, G A Chalyĭ
Journal	Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) Issue 5 Pg. 90-5 (May 1988) ISSN: 0372-9311 [Print] Russia (Federation)
Vernacular Title	Vliianie terrilitina na aktivnost' faktorov nespetsificheskoĭ rezistentnosti pri immunizatsii stafilokokkovom anatoksinom i infitsirovanii stafilokokkom.
PMID	2458002 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References	Anti-Bacterial Agents Antibodies, Bacterial Drug Combinations Enzymes, Immobilized Staphylococcal Toxoid amylase, phosphates, proteases drug combinations Amylases Peptide Hydrolases
Topics	Amylases (therapeutic use) Animals Anti-Bacterial Agents (therapeutic use) Antibodies, Bacterial (analysis) Drug Combinations (therapeutic use) Drug Evaluation, Preclinical Enzymes, Immobilized (therapeutic use) Immunity, Innate (drug effects) Immunization Peptide Hydrolases (therapeutic use) Phagocytosis (drug effects) Rabbits Rats Rats, Inbred Strains Staphylococcal Infections (drug therapy, immunology) Staphylococcal Toxoid (immunology) Staphylococcus (immunology) Time Factors

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