Phytoestrogens exist in edible compounds commonly found in fruits or plants. For long times,
phytoestrogens have been used for therapeutic treatments against human diseases, and they can be promising ingredients for future pharmacological industries.
Kaempferol is a yellow compound found in grapes, broccoli and yellow fruits, which is one of
flavonoid as
phytoestrogens.
Kaempferol has been suggested to have an
antioxidant and anti-inflammatory effect. In past decades, many studies have been performed to examine anti-toxicological role(s) of
kaempferol against human
cancers. It has been shown that
kaempferol may be involved in the regulations of cell cycle,
metastasis, angiogenesis and apoptosis in various
cancer cell types. Among them, there have been a few of the studies to examine a relationship between
kaempferol and apoptosis. Thus, in this review, we highlight the effect(s) of
kaempferol on the regulation of apoptosis in diverse
cancer cell models. This could be a forecast in regard to use of
kaempferol as promising treatment against human diseases.