Abstract | OBJECTIVE: Fibrolamellar hepatocellular carcinoma (HCC) is a rare primary liver tumor, which significantly differs from conventional HCC. This article reviews the molecular cytogenetics, pathology, imaging features, and management of this relatively rare tumor. CONCLUSION: Fibrolamellar HCC predominantly occurs in young patients without underlying hepatitis or cirrhosis. Serum α-fetoproteins are not elevated in most cases, and hence imaging plays an important role in diagnosis, staging, and surveillance.
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Authors | Dhakshinamoorthy Ganeshan, Janio Szklaruk, Vikas Kundra, Ahmed Kaseb, Asif Rashid, Khaled M Elsayes |
Journal | AJR. American journal of roentgenology
(AJR Am J Roentgenol)
Vol. 202
Issue 3
Pg. 544-52
(Mar 2014)
ISSN: 1546-3141 [Electronic] United States |
PMID | 24555590
(Publication Type: Comparative Study, Journal Article, Review)
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Topics |
- Adolescent
- Adult
- Carcinoma, Hepatocellular
(diagnosis)
- Female
- Humans
- Liver Neoplasms
(diagnosis)
- Magnetic Resonance Imaging
(methods)
- Male
- Positron-Emission Tomography
(methods)
- Tomography, X-Ray Computed
(methods)
- Ultrasonography
(methods)
- Young Adult
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