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Imaging features of fibrolamellar hepatocellular carcinoma.

AbstractOBJECTIVE:
Fibrolamellar hepatocellular carcinoma (HCC) is a rare primary liver tumor, which significantly differs from conventional HCC. This article reviews the molecular cytogenetics, pathology, imaging features, and management of this relatively rare tumor.
CONCLUSION:
Fibrolamellar HCC predominantly occurs in young patients without underlying hepatitis or cirrhosis. Serum α-fetoproteins are not elevated in most cases, and hence imaging plays an important role in diagnosis, staging, and surveillance.
AuthorsDhakshinamoorthy Ganeshan, Janio Szklaruk, Vikas Kundra, Ahmed Kaseb, Asif Rashid, Khaled M Elsayes
JournalAJR. American journal of roentgenology (AJR Am J Roentgenol) Vol. 202 Issue 3 Pg. 544-52 (Mar 2014) ISSN: 1546-3141 [Electronic] United States
PMID24555590 (Publication Type: Comparative Study, Journal Article, Review)
Topics
  • Adolescent
  • Adult
  • Carcinoma, Hepatocellular (diagnosis)
  • Female
  • Humans
  • Liver Neoplasms (diagnosis)
  • Magnetic Resonance Imaging (methods)
  • Male
  • Positron-Emission Tomography (methods)
  • Tomography, X-Ray Computed (methods)
  • Ultrasonography (methods)
  • Young Adult

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