Stevens Johnson Syndrome associated with Lamotrigine.

Abstract

Stevens-Johnsons Syndrome (SJS) is an immune-complex-mediated hypersensitivity reaction and has been linked as an adverse side effects to many drugs. Lamotrigine, an anticonvulsive medication and also a commonly used mood stabiliser, can be associated with this adverse reaction. Although this has not been reported very commonly , SJS has high mortality and morbidity and requires careful attention as the use of Lamotrigine is increasing in clinical practice. We present a case where the patient developed Stevens - Johnson Syndrome three weeks after being started on Lamotrigine. The case is discussed for its relevance to the use of Lamotrigine which is currently prescribed very commonly in psychiatric practices.

• Authors: Shama Parveen, M Afzal Javed
• Journal: Pakistan journal of medical sciences (Pak J Med Sci) Vol. 29 Issue 6 Pg. 1450-2 (Nov 2013) ISSN: 1682-024X [Print] Pakistan
• PMID: 24550973 (Publication Type: Case Reports)