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Gadolinium-enriched polyaniline particles (GPAPs) for simultaneous diagnostic imaging and localized photothermal therapy of epithelial cancer.

Abstract
By loading Gd(III) inside NIR-absorbing polyaniline nanostructures, a novel diagnostic and photothermal agent with enhanced MR sensitivity, targeting ability, and photothermal ability to treat epithelial cancer is developed.
AuthorsTaeksu Lee, Doyeon Bang, Yeonji Park, Sun Hee Kim, Jihye Choi, Joseph Park, Donghun Kim, Eunkyoung Kim, Jin-Suck Suh, Yong-Min Huh, Seungjoo Haam
JournalAdvanced healthcare materials (Adv Healthc Mater) Vol. 3 Issue 9 Pg. 1408-14 (Sep 2014) ISSN: 2192-2659 [Electronic] Germany
PMID24550214 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Copyright© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Chemical References
  • Aniline Compounds
  • Contrast Media
  • polyaniline
  • Gadolinium
Topics
  • Aniline Compounds (chemistry, therapeutic use)
  • Animals
  • Cell Line
  • Contrast Media (chemistry, therapeutic use)
  • Diagnostic Imaging (methods)
  • Gadolinium (chemistry, therapeutic use)
  • Humans
  • Hyperthermia, Induced (instrumentation, methods)
  • Magnetic Resonance Imaging
  • Mice
  • Neoplasms, Glandular and Epithelial (drug therapy, pathology)
  • Xenograft Model Antitumor Assays

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