Retinal pigment epithelium tear formation following intravitreal ranibizumab injection in choroidal neovascularization secondary to choroidal osteoma.

Abstract	Choroidal osteoma is an extremely rare osseous tumor of the choroid where choroidal neovascularization (CNV) is the major cause of visual loss. We report the case of a 28-year-old female with CNV secondary to choroidal osteoma, who developed RPE tear after intravitreal ranibizumab treatment.
Authors	Muhammet K Erol, Deniz Turgut Coban, Basak Bostanci Ceran, Mehmet Bulut
Journal	Cutaneous and ocular toxicology (Cutan Ocul Toxicol) Vol. 33 Issue 3 Pg. 259-63 (Sep 2014) ISSN: 1556-9535 [Electronic] England
PMID	24517498 (Publication Type: Case Reports, Journal Article)
Chemical References	Angiogenesis Inhibitors Antibodies, Monoclonal, Humanized Ranibizumab
Topics	Adult Angiogenesis Inhibitors (administration & dosage, adverse effects) Antibodies, Monoclonal, Humanized (administration & dosage, adverse effects) Choristoma (complications, drug therapy, pathology) Choroid Neoplasms (complications, drug therapy, pathology) Choroidal Neovascularization (drug therapy, pathology) Female Humans Intravitreal Injections (adverse effects) Osteoma (complications, drug therapy, pathology) Ranibizumab Retinal Perforations (etiology) Retinal Pigment Epithelium (pathology)

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