Abstract | OBJECTIVE: The incidence and risk factors for vasoplegia in the early postoperative period and at 24h are investigated in patients subjected to cardiopulmonary bypass surgery. Vasoplegia following cardiac surgery with cardiopulmonary bypass is associated with a high morbimortality. The risk factors described emerged from retrospective, non-controlled studies. METHODS: Observational prospective study of 188 consecutive patients subjected to cardiac surgery with cardiopulmonary bypass in a single hospital between November 2011 and May 2012. Emergency surgery or complex procedures were excluded. Vasoplegia was assessed during the immediate postoperative period, and at 24h after surgery, and was defined as a mean arterial pressure below 50mmHg, and the need for a noradrenaline perfusion of more than 0.08μg/kg/min, monitored by cardiac output and systemic vascular resistances. The anaesthetic and cardiopulmonary bypass protocols, as well as haemodynamic management, were the same in all patients. RESULTS: CONCLUSION:
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Authors | M Durán Bruce, C Gomar Sancho, J C Holguera, E Muliterno Español |
Journal | Revista espanola de anestesiologia y reanimacion
(Rev Esp Anestesiol Reanim)
Vol. 61
Issue 5
Pg. 246-53
(May 2014)
ISSN: 2340-3284 [Electronic] Spain |
Vernacular Title | Factores implicados en el desarrollo de vasoplejía tras cirugía cardiaca con circulación extracorpórea. Estudio prospectivo observacional. |
PMID | 24507583
(Publication Type: Journal Article, Observational Study)
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Copyright | Copyright © 2013 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Published by Elsevier España. All rights reserved. |
Chemical References |
- Angiotensin-Converting Enzyme Inhibitors
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Topics |
- Aged
- Angiotensin-Converting Enzyme Inhibitors
(adverse effects, therapeutic use)
- Cardiac Surgical Procedures
- Cardiopulmonary Bypass
(adverse effects)
- Constriction
- Extracorporeal Membrane Oxygenation
(adverse effects)
- Female
- Hemodynamics
- Humans
- Hypothermia
(complications)
- Incidence
- Male
- Middle Aged
- Premedication
(adverse effects)
- Prospective Studies
- Risk Factors
- Stroke Volume
- Time Factors
- Vasoplegia
(epidemiology, etiology, physiopathology)
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