Abstract | BACKGROUND: METHODS: The medical records and radiographs of 316 patients with osteogenesis imperfecta were retrospectively reviewed. The severity of osteogenesis imperfecta was classified with the modified Sillence classification. Serial curve measurements were recorded throughout the follow-up period for each patient with scoliosis. Regression analysis was used to determine the effect of disease severity (Sillence type), patient age, and bisphosphonate treatment on the progression of scoliosis as measured with the Cobb method. RESULTS: CONCLUSIONS:
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Authors | Alireza K Anissipour, Kim W Hammerberg, Angela Caudill, Theodore Kostiuk, Sergey Tarima, Heather Shi Zhao, Joseph J Krzak, Peter A Smith |
Journal | The Journal of bone and joint surgery. American volume
(J Bone Joint Surg Am)
Vol. 96
Issue 3
Pg. 237-43
(Feb 05 2014)
ISSN: 1535-1386 [Electronic] United States |
PMID | 24500586
(Publication Type: Journal Article, Research Support, N.I.H., Extramural)
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Topics |
- Adolescent
- Age Factors
- Child
- Child, Preschool
- Disease Progression
- Female
- Growth
(physiology)
- Humans
- Infant
- Male
- Osteogenesis Imperfecta
(complications, physiopathology, surgery)
- Retrospective Studies
- Scoliosis
(complications, physiopathology, surgery)
- Treatment Outcome
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