[Different methods for the diagnosis of endometrial histological comparative study].

Abstract

OBJECTIVE:

To evaluate the feasibility of endometrial sampler Pipelle for endometrial histologic diagnosis.

METHODS:

Using prospective and self-control methods, 200 patients with endometrial biopsy firstly used Pipelle endometrial sampler for endometrial tissue, then followed by diagnostic curettage, the same pathologist evaluated the specimen quality and made the histologic diagnosis.

RESULTS:

Totally 200 patients completed the observation, the specimen satisfaction of Pipelle was 93.0% (in this 200 cases, 186 cases were satisfactory), its pathological accuracy was 85.0% (in this 200 cases, 170 cases' pathological results are highly consistent with diagnostic curettage). There was no significant difference between two kinds of endometrial sampling (P > 0.05). There was no pain for patients during the Pipelle using process.

CONCLUSION:

Pipelle could obtain satisfactory samples used for histological diagnosis in normal endometrium, simple hyperplasia, complex hyperplasia, atypical hyperplasia and endometrial cancer disease, because its pathological accuracy is so close to the diagnostic curettage, which may be used as a routine screening tool of endometrial diseases.

• Authors: Xu Leng, Min Wang, Shu-lan Zhang, Dan Wang, Wei Cao, Xiang-hong Yang
• Journal: Zhonghua fu chan ke za zhi (Zhonghua Fu Chan Ke Za Zhi) Vol. 48 Issue 12 Pg. 891-5 (Dec 2013) ISSN: 0529-567X [Print] China
• PMID: 24495679 (Publication Type: Comparative Study, English Abstract, Journal Article)

Topics

• Biopsy (instrumentation, methods)
• Dilatation and Curettage
• Endometrial Hyperplasia (diagnosis, pathology)
• Endometrial Neoplasms (diagnosis, pathology)
• Endometrium (pathology)
• Female
• Humans
• Predictive Value of Tests
• Prospective Studies
• Sensitivity and Specificity
• Specimen Handling (instrumentation, methods)
• Vacuum Curettage (instrumentation, methods)