[Treating HIV/AIDS patients by shenlin fuzheng capsule and qingdu capsule: an analysis of clinical effectiveness].

Abstract

OBJECTIVE:

To analyze the clinical effectiveness of Shenling Fuzheng Capsule (SFC) and Qingdu Capsule (QC) in treating HIV/AIDS patients.

METHODS:

Totally 220 patients with complete clinical data, who received consecutive treatment for 6 months were selected from the database. They were assigned to two groups whether they would rather receive antiretroviral drugs, the Chinese medicine (CM) treatment group and the integrative medicine (IM) group. The 129 patients in the CM group were treated with SFC or QC, while the 91 patients in the IM group were treated with SFC or QC combined highly active antiretroviral agents. Total score and single score of clinical symptoms and signs, Karnofsky Performance Status (KPS), and changes of body weight before treatment, 3 and 6 months after treatment were compared. CD4+ cell counts were compared between before treatment and 6 months after treatment.

RESULTS:

The total score of clinical symptoms and signs were lower at 3 and 6 months of treatment than before treatment respectively (P < 0.01). The single score of clinical symptoms and signs such as cough, weakness, shortness of breath, vomit, spontaneous perspiration, hair loss,and chest pain were also lowered at 3 and 6 months of treatment (P < 0.05, P < 0.01), and the KPS increased (P < 0.05). The body weight increased (P < 0.05) and CD4 cell counts decreased (P < 0.05) in the CM group. There was no statistical difference in body weight or CD4 cell counts in the IM group between before and after treatment.

CONCLUSION:

SFC and QC could improve clinical symptoms and signs of HIV/ AIDS patients, but failed to deter the decrease of CD4+ cell counts.

• Authors: Qi-jian Su, Yi-zhong Li, Wei-qun Wu, Zhen-zhen Lu, Ya-ping Zhang, Zhen-wei Liu, Xuan Li, Xin Deng
• Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine (Zhongguo Zhong Xi Yi Jie He Za Zhi) Vol. 33 Issue 11 Pg. 1476-80 (Nov 2013) ISSN: 1003-5370 [Print] China
• PMID: 24483106 (Publication Type: Controlled Clinical Trial, English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Retroviral Agents
• Capsules
• Drugs, Chinese Herbal
• qingdu

Topics

• Acquired Immunodeficiency Syndrome (drug therapy)
• Adolescent
• Adult
• Aged
• Anti-Retroviral Agents (therapeutic use)
• CD4 Lymphocyte Count
• Capsules
• Drugs, Chinese Herbal (therapeutic use)
• Female
• Humans
• Male
• Middle Aged
• Phytotherapy
• Young Adult