HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Systemic toxicity to local anesthesia in an infant undergoing circumcision.

Abstract
A circumcision was planned for a four-month-old infant under local anesthesia. After the application of lidocaine, the infant stopped crying, and then generalized tonic-clonic convulsions and a diffuse erythematous rash developed. The patient was immediately monitored, ventilation was provided, and 1 mg midazolam was given intramuscularly. After insertion of a cannula, sodium thiopental 50 mg was given intravenously, the patient's convulsions were controlled, and endotracheal intubation was performed. The patient was extubated 30 minutes later. However, the patient was re-intubated due to his noisy breathing, and 10 mg prednisolone was given intravenously due to mild edema seen in the larynx during endotracheal intubation. Two hours after the second intubation, the patient started to breath spontaneously and opened his eyes; he was extubated and transferred to the intensive care unit. Two days later the patient was discharged. Systemic toxicity to the local anesthesia was considered in this patient. All precautions need to be considered during the application of local anesthesia in pediatric patients, including proper indication, monitoring of the patient in the preoperative period, establishment of venous access, and readiness to apply cardiopulmonary resuscitation in the event of local anesthetic toxicity. The maximum dose of local anesthesia should be considered and it should be diluted during application.
AuthorsAyşe Belin Özer, Ömer Lütfi Erhan
JournalAgri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology (Agri) Vol. 26 Issue 1 Pg. 43-6 ( 2014) ISSN: 2458-9446 [Electronic] Turkey
PMID24481584 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anesthetics, Local
  • Lidocaine
Topics
  • Anesthetics, Local (adverse effects)
  • Circumcision, Male (methods)
  • Diagnosis, Differential
  • Humans
  • Infant
  • Lidocaine (adverse effects)
  • Male
  • Seizures (chemically induced, diagnosis)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: