[The proinsulin level in the blood of children with type 1 diabetes mellitus of various duration].

Abstract

Proinsulin content was measured in the serum of 82 children (aged from 3 to 14 years) with type 1 diabetes mellitus of various duration. Three groups of patients characterized by low (54%), normal (42%) and high (4%) levels of this prohormone were recognized. No dependence the proinsulin level on the disease term was found. The serum proinsulin level may be used as a parameter specifying the pathogenesis of type 1 diabetes mellitus.

• Authors: N Iu Lotosh, A A Selishcheva, S A Nadorov, B A Badyshtov, I É Volkov, S V Savel'ev
• Journal: Biomeditsinskaia khimiia (Biomed Khim) 2013 Sep-Oct Vol. 59 Issue 5 Pg. 563-9 ISSN: 2310-6972 [Print] Russia (Federation)
• PMID: 24479346 (Publication Type: English Abstract, Journal Article)

Chemical References

• Biomarkers
• Proinsulin

Topics

• Adolescent
• Adult
• Biomarkers (blood)
• Child
• Child, Preschool
• Diabetes Mellitus, Type 1 (blood)
• Female
• Humans
• Male
• Proinsulin (blood)
• Time Factors