Effect of natural gel product on bovine dentin erosion in vitro.

Abstract

OBJECTIVE:

To evaluate the efficacy of Neem (Azadirachta indica) experimental gel for the prevention of erosive wear on bovine dentin, in vitro.

MATERIAL AND METHODS:

One hundred dentin blocks were allocated into 5 experimental groups (20 samples each): C (control group, without gel); CG (control group, only base gel); F (fluoride gel, 1.23% NaF; pH 4.1, Dentsply; Brazil); N (Neem gel, 10% neem extract; pH 4.1, manipulation); NF (Neem+fluoride gel, 10% Neem extract and 1.23% NaF; pH 4.1, manipulation). The blocks were stored in artificial saliva for 24 hours. After this, they were submitted to six alternating re- and demineralization cycles. The blocks were analyzed for wear (profilometry). The results were submitted to statistical analysis by ANOVA and Tukey tests (P<0.05).

RESULTS:

The mean wear (±SD, µm) was shown as follows in groups: C (13.09±0.99), CG (10.60±1.99), F (10.90±1.44), N (12.68±1.13) and NF (10.84±1.65). All gels showed some preventive action when compared with control group. However, significant differences were found only between Neem+fluoride gel and fluoride gel.

CONCLUSION:

A single application of a neem-containing fluoride gel reduced dentin erosion, thus it is a possible alternative in reducing dental wear. Further research should investigate the action mechanism and the synergism between them.

• Authors: André de Carvalho Sales-Peres, Juliane Avansini Marsicano, Rudan Paraíso Garcia, Moacir Rossi Forim, Maria Fatima das Graças Fernandes da Silva, Sílvia Helena de Carvalho Sales-Peres
• Journal: Journal of applied oral science : revista FOB (J Appl Oral Sci) 2013 Nov-Dec Vol. 21 Issue 6 Pg. 597-600 ISSN: 1678-7765 [Electronic] Brazil
• PMID: 24473728 (Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Fluorides, Topical
• Gels
• Plant Extracts
• Saliva, Artificial

Topics

• Animals
• Azadirachta (chemistry)
• Cattle
• Dental Enamel (drug effects)
• Dentin (drug effects)
• Fluorides, Topical (pharmacology, therapeutic use)
• Gels
• Hardness
• Plant Extracts (pharmacology, therapeutic use)
• Reproducibility of Results
• Saliva, Artificial (chemistry)
• Surface Properties
• Time Factors
• Tooth Demineralization
• Tooth Erosion (prevention & control)
• Tooth Remineralization