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Bone loss at implant with titanium abutments coated by soda lime glass containing silver nanoparticles: a histological study in the dog.

Abstract
The aim of the present study was to evaluate bone loss at implants connected to abutments coated with a soda-lime glass containing silver nanoparticles, subjected to experimental peri-implantitis. Also the aging and erosion of the coating in mouth was studied. Five beagle dogs were used in the experiments. Three implants were placed in each mandible quadrant: in 2 of them, Glass/n-Ag coated abutments were connected to implant platform, 1 was covered with a Ti-mechanized abutment. Experimental peri-implantitis was induced in all implants after the submarginal placement of cotton ligatures, and three months after animals were euthanatized. Thickness and morphology of coating was studied in abutment cross-sections by SEM. Histology and histo-morphometric studies were carried on in undecalfied ground slides. After the induced peri-implantitis: 1.The abutment coating shown losing of thickness and cracking. 2. The histometry showed a significant less bone loss in the implants with glass/n-Ag coated abutments. A more symmetric cone of bone resorption was observed in the coated group. There were no significant differences in the peri-implantitis histological characteristics between both groups of implants. Within the limits of this in-vivo study, it could be affirmed that abutments coated with biocide soda-lime-glass-silver nanoparticles can reduce bone loss in experimental peri-implantitis. This achievement makes this coating a suggestive material to control peri-implantitis development and progression.
AuthorsArturo Martinez, Francisco Guitián, Roberto López-Píriz, José F Bartolomé, Belén Cabal, Leticia Esteban-Tejeda, Ramón Torrecillas, José S Moya
JournalPloS one (PLoS One) Vol. 9 Issue 1 Pg. e86926 ( 2014) ISSN: 1932-6203 [Electronic] United States
PMID24466292 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Calcium Compounds
  • Dental Implants
  • Oxides
  • Silver
  • lime
  • Titanium
Topics
  • Alveolar Bone Loss (etiology, pathology)
  • Animals
  • Calcium Compounds
  • Dental Abutments
  • Dental Implants (adverse effects)
  • Dogs
  • Glass
  • Metal Nanoparticles (adverse effects, chemistry)
  • Oxides
  • Peri-Implantitis (physiopathology)
  • Silver
  • Titanium

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