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[Successful treatment of rhino-orbital-cerebral mucormycosis in a kidney transplant patient].

Abstract
Rhino-orbital-cerebral mucormycosis is a potentially fatal mycotic infection in immunosuppressed patients. The main risk factors for acquiring this infection are poorly controlled diabetes mellitus, iron overload, potent immunosuppression and chronic steroid use. In this review, we present the case of a kidney transplant patient who, after treatment of an acute rejection episode with high doses of steroids and potent immunosuppression with tacrolimus and mycophenolate, presented with rapidly progressing rhino-orbital-cerebral mucormycosis that required aggressive surgical treatment, immunosuppression discontinuation and potent antifungal treatment.
AuthorsJohn F Nieto-Ríos, Luis F Moreno-Coral, Andrés Zapata-Cárdenas, Catalina Ocampo-Kohn, Arbey Aristizabal-Alzate, Lina M Serna-Higuita, Isabel C Ramírez-Sánchez, Gustavo A Zuluaga-Valencia
JournalNefrologia : publicacion oficial de la Sociedad Espanola Nefrologia (Nefrologia) Vol. 34 Issue 1 Pg. 120-4 ( 2014) ISSN: 1989-2284 [Electronic] Spain
Vernacular TitleTratamiento exitoso de mucormicosis rino-órbito-cerebral en un paciente trasplantado renal.
PMID24463869 (Publication Type: Case Reports, English Abstract, Journal Article)
Topics
  • Adult
  • Brain Diseases (microbiology, therapy)
  • Central Nervous System Fungal Infections (microbiology, therapy)
  • Humans
  • Kidney Transplantation
  • Male
  • Mucormycosis (therapy)
  • Nose Diseases (microbiology, therapy)
  • Orbital Diseases (microbiology, therapy)
  • Postoperative Complications (microbiology, therapy)
  • Remission Induction

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